Targeted Protein Degradation Market: Riding on the Popularity of PROTAC, Market is set to Grow Exponentially

Over the years, the drug hunters have tried to target the tens of thousands of proteins responsible for sickness and health. But a vast majority of them have remained out of reach. While the scientific evolution has led to the development of potent and selective small-molecule inhibitors of protein function, but still, multiple targets of high biomedical relevance are highly challenging targets for typical small-molecule drugs. Similarly, the novel biologics, such as oligonucleotides and monoclonal antibodies have although allowed us to target some of these difficult to reach proteins, their delivery to the target site has created challenges of its own. In this article, we will evaluate the rising popularity of the concept of targeted protein degradation in overcoming the aforementioned challenges.

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